I saw elsewhere - perhaps Twitter - a criticism of the #cyberpunk idea, reflected in Cyberpunk 2077, that the unaltered human body is somehow sacred, and that augmenting it is profane. The criticism noted that this was, at its core, transphobic.
The critic then turned the idea on its head into a trans-positive cyberpunk that eschewed "humanity" in favor of "essence". Maybe one person's essence is complete when they're born; maybe another's essence is lacking until they augment themselves.
@noelle That reminds me of _Glasshouse_ by Charlie Stross. A bunch of people damaged by participating in war, where their minds were inserted into tanks and other inhuman things, mostly wanting baseline human forms for themselves -- but forms they chose. And they accept people who want something different; they just mostly want to feel as human as possible, and they choose bodies that help them do that.